HSCI submitted documents to conduct a clinical trial of the COVID-19 vaccine

HSCI shares: review.

PJSC HSCI (Human Stem Cell Institute) is a Russian biotechnology company. Created in 2003, converted from an open joint stock company to a public company in 2015. Works in the fields of regenerative medicine, bioinsurance, medical genetics, gene therapy, and biopharmaceuticals.

Conducts scientific research and is engaged in the development, commercialization and further promotion of its own innovative medicines on the market, provides CRO and CMO - Russia's largest bank for personal storage of umbilical cord blood stem cells, containing more than 23 thousand samples, and Reprobank - a high-tech bank for storage of reproductive cells person.

In 2011, it introduced an innovative aesthetic medicine service to the market - SPRS therapy, which uses dermal autofibroblasts to correct skin defects. In January 2012, he began implementing the Gemaskrin program for the early detection and prevention of hereditary diseases through medical and genetic counseling. Since September 2012, it has opened sales of Neovasculgen, the first Russian gene therapy drug for the treatment of chronic ischemia of the lower extremities of atherosclerotic origin. The drug is registered in Russia and Ukraine.

HSCI is the largest non-state co-investor of the multilateral project SynBio for the development and production of unique medicines for the Russian and world markets. It is implementing the socially significant project Genetico to create a laboratory for new methods of genetic diagnostics and a nationwide network of medical centers providing genetic diagnostics and counseling services. In December 2009, it became the first Russian biotechnology company to publicly list shares on the Moscow Exchange.

OKVED codes

PJSC HSCI has the right to engage in 18 types of activities. Main type of activity

Additional activities

HSCI submitted documents to conduct a clinical trial of the COVID-19 vaccine

, owned by the Human Stem Cell Institute (HSCI), submitted an application to the Russian Ministry of Health for permission to conduct a clinical trial (CT) of its vaccine against COVID-19. Preclinical studies of Betuvax-CoV-2 have shown the effectiveness of the drug, the developers say.

“We count on effective interaction with the Ministry of Health in the process of obtaining permission.<...> We hope that our vaccine can be registered along with government developments, and a vaccine created by a private biotech will appear in Russia. Betuvax-CoV-2 is technologically significantly different from already registered vaccines and, in the opinion of our team, may be especially in demand for people with chronic and autoimmune diseases, for children and the elderly, as well as for repeated, so-called booster vaccinations,” said the Chairman of the Board of Directors of HSCI Artur Isaev.

Director Anna Vakhrusheva explained that the drug is the first new generation recombinant vaccine in Russia based on spherical particles made from natural material that imitate viral particles containing the surface antigen (protein) of SARS-CoV-2. According to her, the vaccine is not integrated into the body’s cells and does not carry an excess antigenic load.

HSCI's plans to invest in the development became known in February 2021. Then it was planned to invest 45 million rubles in the project - to complete preclinical trials, clinical trials and the production of Betuvax-CoV-2. In April 2021, the Moscow Venture Investment Development Fund (Moscow Seed Fund) allocated 36 million rubles to conduct research necessary for state registration and bringing the COVID-19 vaccine to the market.

Several vaccines against coronavirus infection have already been registered in Russia: Sputnik V and Sputnik Light from NICEM. N.F. Gamaleya, EpiVacCorona from the State Scientific and CoviVac from the Center named after. M.P. Chumakova.

According to SPARK-Interfax, Betuvax LLC was registered in Moscow on August 24, 2021. The company is engaged in research and development in the field of biotechnology. HSCI owns 100% of the company.

HSCI is a Russian public company founded in 2003, specializing in biomedical technologies. The holding's revenue in 2021 amounted to 1.084 billion rubles, which is 29.7% more than in 2019. A third of the total cash flow came from the revenue of one of the Genetico holding structures.

Source HSCI

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LLC "TSGRM "GENETICO"

• OGRN:
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• 143026, Moscow, territory of the Skolkovo Innovation Center, Bolshoi Boulevard, 42, building 1, floor 1 room. 334 workers months 52

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LLC "SKINTSEL"

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LLC "CENTRAL BANK OF STEM CELLS"

• OGRN:
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LLC "HISTOGRAFT"

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LLC "ICEGEN 2"

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"ICEGEN" LLC

• OGRN:
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OOO "ANGIOGENESIS"

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LLC "NVG-CARDIO"

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NEXTGEN LLC

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LLC "GENE AND CELLS"

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2020

• 03.04.2020
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2019

• 26.06.2019
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  12101

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Documentation:

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• 01.04.2019
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  9197746516816
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  12201

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Documentation:

• Application on form p14001
• Minutes of the general meeting of legal entities participants

• 08.02.2019
• GRN
  6197746555320
• SPVZ code

  13300

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission of information on registration of a legal entity as an insurer in the territorial body of the Pension Fund of the Russian Federation

2018

• 30.10.2018
• GRN
  8187749627926
• SPVZ code

  13106

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the recognition of the license as invalid

• 30.10.2018
• GRN
  8187749627893
• SPVZ code

  13102

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the re-issuance of documents confirming the availability of a license (information on the extension of the license validity period)

• 30.10.2018
• GRN
  8187749627783
• SPVZ code

  13102

• Code NO

  7746

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  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the re-issuance of documents confirming the availability of a license (information on the extension of the license validity period)

• 07.09.2018
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  9187748670122
• SPVZ code

  13300

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission of information on registration of a legal entity as an insurer in the territorial body of the Pension Fund of the Russian Federation

• 07.09.2018
• GRN
  9187748667383
• SPVZ code

  13300

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission of information on registration of a legal entity as an insurer in the territorial body of the Pension Fund of the Russian Federation

• 27.08.2018
• GRN
  9187748156125
• SPVZ code

  13200

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission of information on registration of a legal entity with the tax authority

• 27.08.2018
• GRN
  9187748156114
• SPVZ code

  13200

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission of information on registration of a legal entity with the tax authority

• 27.08.2018
• GRN
  9187748159546
• SPVZ code

  12101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

State registration of changes made to the constituent documents of a legal entity related to changes to information about a legal entity contained in the Unified State Register of Legal Entities, based on an application

Documentation:

• P13001 statement on changes made to the constituent documents
• Document confirming payment of state duty dated July 23, 2018
• Charter of the legal entity in the new edition
• Minutes of the general meeting of legal entities participants
• Envelope

• 27.08.2018
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  9187748151527
• SPVZ code

  12201

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Changing information about a legal entity contained in the Unified State Register of Legal Entities

Documentation:

• P14001 application for changes in information not related to changes. constituent documents (clause 2.1)
• Letter of guarantee, St. Vo, agreement 39

• 06.06.2018
• GRN
  2187748768755
• SPVZ code

  13801

• Code NO

  7746

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Submission of information on the issuance or replacement of identity documents of a citizen of the Russian Federation on the territory of the Russian Federation

• 18.05.2018
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  9187747795160
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  13106

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

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• 21.04.2018
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• SPVZ code

  13106

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  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

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• 13.04.2018
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• SPVZ code

  13801

• Code NO

  7746

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Submission of information on the issuance or replacement of identity documents of a citizen of the Russian Federation on the territory of the Russian Federation

• 20.03.2018
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  7746

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Changing information about a legal entity contained in the Unified State Register of Legal Entities

Documentation:

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  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

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Documentation:

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• Charter of the legal entity in the new edition
• Decision to amend the constituent documents (protocol)
• Power of attorney for Leontiev I.S.

• 02.05.2017
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• Code NO

  7746

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Changing information about a legal entity contained in the Unified State Register of Legal Entities

Documentation:

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2016

• 18.09.2016
• GRN
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• Code NO

  7746

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Submission of information on registration of a legal entity as an insurer in the executive body of the Social Insurance Fund of the Russian Federation

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• 16.12.2015
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  15303

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• 16.12.2015
• GRN
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• SPVZ code

  13106

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the recognition of the license as invalid

• 15.12.2015
• GRN
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• SPVZ code

  15303

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Recognition of an entry entered into the Unified State Register of Legal Entities in relation to a legal entity containing information received from another body as invalid on the basis of a message received from the said body

• 15.12.2015
• GRN
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• SPVZ code

  13106

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the recognition of the license as invalid

• 15.12.2015
• GRN
  6157748116872
• SPVZ code

  15303

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Recognition of an entry entered into the Unified State Register of Legal Entities in relation to a legal entity containing information received from another body as invalid on the basis of a message received from the said body

• 15.12.2015
• GRN
  6157748115740
• SPVZ code

  13106

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the recognition of the license as invalid

• 08.07.2015
• GRN
  2157747728884
• SPVZ code

  15101

• Code NO

  7746

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Making changes to information about a legal entity contained in the Unified State Register of Legal Entities due to errors made by the registration authority

Documentation:

• Act
• The decision to amend the Unified State Register of Legal Entities due to errors made

• 29.06.2015
• GRN
  2157747286167
• SPVZ code

  12101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

State registration of changes made to the constituent documents of a legal entity related to changes to information about a legal entity contained in the Unified State Register of Legal Entities, based on an application

Documentation:

• P13001 statement on changes made to the constituent documents
• Document confirming payment of state duty dated June 23, 2015
• Charter of the legal entity in the new edition
• Decision to amend the constituent documents/protocol/
• Power of attorney

• 03.06.2015
• GRN
  9157746391090
• SPVZ code

  13101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the granting of a license

• 21.05.2015
• GRN
  8157746766378
• SPVZ code

  13105

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on license revocation

• 21.05.2015
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• SPVZ code

  13105

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on license revocation

• 20.05.2015
• GRN
  8157746727306
• SPVZ code

  13105

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on license revocation

• 23.01.2015
• GRN
  2157746403000
• SPVZ code

  13102

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the re-issuance of documents confirming the availability of a license (information on the extension of the license validity period)

• 17.01.2015
• GRN
  2157746320103
• SPVZ code

  13101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the granting of a license

2014

• 31.10.2014
• GRN
  2147748243025
• SPVZ code

  13101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the granting of a license

• 31.10.2014
• GRN
  2147748242410
• SPVZ code

  13102

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the re-issuance of documents confirming the availability of a license (information on the extension of the license validity period)

• 10.07.2014
• GRN
  6147747351724
• SPVZ code

  12101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

State registration of changes made to the constituent documents of a legal entity related to changes to information about a legal entity contained in the Unified State Register of Legal Entities, based on an application

Documentation:

• P13001 statement on changes made to the constituent documents
• Legal entity charter
• Document confirming payment of state duty dated 07/01/2014
• Decision to amend the constituent documents
• Power of attorney

• 24.04.2014
• GRN
  8147746885102
• SPVZ code

  12201

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Changing information about a legal entity contained in the Unified State Register of Legal Entities

Documentation:

• P14001 application for changes in information not related to changes. constituent documents (clause 2.1)
• Protocol
• Power of attorney

2013

• 31.05.2013
• GRN
  9137746517042
• SPVZ code

  12201

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Changing information about a legal entity contained in the Unified State Register of Legal Entities

Documentation:

• P14001 application for changes in information not related to changes. constituent documents (clause 2.1)
• Power of attorney, envelope

• 01.03.2013
• GRN
  6137746527341
• SPVZ code

  13101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the granting of a license

2011

• 19.05.2011
• GRN
  8117746674059
• SPVZ code

  13101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission by the licensing authority of information on the granting of a license

2010

• 16.07.2010
• GRN
  8107747920305
• SPVZ code

  12101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

State registration of changes made to the constituent documents of a legal entity related to changes to information about a legal entity contained in the Unified State Register of Legal Entities, based on an application

Documentation:

• P13001 statement on changes made to the constituent documents
• Document confirming payment of state duty dated June 24, 2010
• Charter of the legal entity dated June 10, 2010
• Report
• Decision to amend the constituent documents dated June 10, 2010
• Letter, request, quit 1830
• Cop. mouth

2009

• 03.11.2009
• GRN
  6097748372375
• SPVZ code

  12101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

State registration of changes made to the constituent documents of a legal entity related to changes to information about a legal entity contained in the Unified State Register of Legal Entities, based on an application

Documentation:

• P13001 statement on changes made to the constituent documents
• Document confirming payment of state duty dated 10/16/2009
• Charter of the legal entity dated September 22, 2009
• Decision to amend the constituent documents dated September 22, 2009
• Power of attorney, envelope, charter, request, receipt

2006

• 19.04.2006
• GRN
  7067746687727
• SPVZ code

  13300

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

Submission of information on registration of a legal entity as an insurer in the territorial body of the Pension Fund of the Russian Federation

• 17.04.2006
• GRN
  7067746637974
• SPVZ code

  12101

• Code NO

  7746

  Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

State registration of changes made to the constituent documents of a legal entity related to changes to information about a legal entity contained in the Unified State Register of Legal Entities, based on an application

Documentation:

• Application (with attachments) dated 04/07/2006
• Charter dated 04/07/2006
• Document confirming payment of state duty dated 04/07/2006
• Decision to amend the constituent documents dated 04/07/2006

2005

• 13.01.2005
• GRN
  2057702009528
• SPVZ code

  12102

• Code NO

  7702

  Inspectorate of the Federal Tax Service No. 2 for Moscow.

Notification of the registration authority about amendments to the constituent documents of a legal entity

Documentation:

• P13002 notification of changes to constituent documents
• Legal entity charter
• Regulations on the organization
• Protocol

2003

• 01.12.2003
• GRN
  —
• SPVZ code

  13200

• Code NO

  7702

  Inspectorate of the Ministry of the Russian Federation for Taxes and Duties No. 2 for the Central Administrative District of Moscow

Submission of information on registration of a legal entity with the tax authority

• 27.11.2003
• GRN
  1037789001315
• SPVZ code

  11201

• Code NO

  7746

  Interdistrict Inspectorate of the Ministry of the Russian Federation for Taxes and Duties No. 46 for Moscow

Creation of a legal entity

Documentation:

• Р11001 application for the creation of a legal entity
• Legal entity charter
• Protocol
• Agreement
• Another document. in accordance with the legislation of the Russian Federation
• Document confirming payment of state duty

brief information

The organization PJSC HSCI was registered on November 27, 2003 by the registrar: Interdistrict Inspectorate of the Federal Tax Service No. 46 for Moscow

.
After registration, the company was assigned: OGRN: 1037789001315, INN: 7702508905 and KPP: 772801001. The main type of activity is “Other activities in the field of medicine, not included in other groups
”, the organization also has 17 additional types of activities. The legal address of PJSC HSCI is 117036, Moscow, 60-Letiya Oktyabrya Ave., 10a, floor 3, room 24.

Address on the map

general information